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Kick the Fly

Kick-the-buddy toy on a live 166,700-neuron MaleCNS. Tools hit real sensory cells; sugar lights PAM dopamine and heals. Reward is the sugar pulse, not a trained game policy.

MaleCNS
Fidelity · reviewed
L2 Plasticity

Synapses change under a modeled rule grounded in fly biology — for example dopamine-gated change on Kenyon-cell → MBON synapses in the mushroom body. Learning begins here.

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The evidence

No evidence, no level.
Rating note

Real dopamine-gated plasticity on the connectome's own synapses, verified to the assignment. The plastic set is the KC->MBON entries of the simulator's synapse matrix itself, located by walking the CSR index arrays; the update depresses them by rate * dopamine * eligibility * weight (floored at 10% of the connectome value, with reversal and a slow decay back toward it), and `_write_back` assigns the result straight into `sim.W_csr.data` / `sim.W_csc.data` — the same matrices the LIF step propagates through. Which DANs gate which MBON, and whether a compartment is PPL1 (punishment) or PAM (reward), is read from the connectome's own DAN->MBON synapse-count matrix, not hand-assigned. It runs live in the brain thread every 10 sim steps during play, not in an offline training script. No validation mark: the rule is grounded in cited fly work (Aso 2014, Hige 2015, Cohn 2015, Felsenberg 2018), but there is no published comparison of this model's behaviour against real fly measurements. The authors also flag which parts are game rules rather than biology — pain driving PPL1, sugar driving PAM, the tool-to-odour mapping, and the learning and forgetting rates.

Record

CategoryGames & control
DatasetsMaleCNS
LevelL2 — reviewed
Listed intownie/awesome-fruit-fly
First indexed2026-09-15

Ratings on thelearningfly.com are proposals, not verdicts. Every one of them is arguable in public.